Summary:
Recombinant human ITGB3BP protein
Cat：P03522
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-177aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ITGB3BP |
| 【Full Name】： integrin beta 3 binding protein (beta3-endonexin) |
| 【Uniprot】： Q13352 |
| 【Gene ID】： 23421 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors.This protein also acts as a corepressor of NF-kappaB-dependent signaling.This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway.This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere.Alternate splicing results in multiple transcript variants.
Verified picture
