Summary:
Recombinant human RAD51C protein
Cat：P03526
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-376aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RAD51C |
| 【Full Name】： RAD51 homolog C (S. cerevisiae) |
| 【Uniprot】： O43502 |
| 【Gene ID】： 5889 |
| 【Species Reactivity】： Human Mouse (A.thaliana) |
| 【Mol Mass】： 42kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene is a member of the RAD51 family.RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA.This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution.Mutations in this gene are associated with Fanconi anemia-like syndrome.This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors.Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression.Alternative splicing results in multiple transcript variants.
Verified picture
