Summary:
Recombinant human CCT5 protein
Cat：P03527
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-350aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CCT5 |
| 【Full Name】： chaperonin containing TCP1，subunit 5 (epsilon) |
| 【Uniprot】： P48643 |
| 【Gene ID】： 22948 |
| 【Species Reactivity】： Human Mouse Rat (Gorilla A.thaliana) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC).This complex consists of two identical stacked rings, each containing eight different proteins.Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner.The complex folds various proteins, including actin and tubulin.Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP).Alternative splicing results in multiple transcript variants.Related pseudogenes have been identified on chromosomes 5 and 13.
Verified picture
