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Recombinant human PHF5A protein

Cat:P03528

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-110aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PHF5A
【Full Name】: PHD finger protein 5A
【Uniprot】: Q7RTV0
【Gene ID】: 84844
【Species Reactivity】: Human Mouse Rat (Fruit fly)
【Mol Mass】: 12kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a subunit of the splicing factor 3b protein complex.Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP).The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA.The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini.This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein.This gene has several pseudogenes on different chromosomes.

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