Summary:
Recombinant human HIST2H4B protein
Cat：P03561
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-103aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： HIST2H4B |
| 【Full Name】： histone cluster 2，H4b |
| 【Uniprot】： P62805 |
| 【Gene ID】： 554313 |
| 【Species Reactivity】： Human |
| 【Mol Mass】： 11kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4).The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family.Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.This gene is found in a histone cluster on chromosome 1.This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Verified picture
