Summary:
Recombinant human DCTD protein
Cat：P03571
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-178aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DCTD |
| 【Full Name】： dCMP deaminase |
| 【Uniprot】： P32321 |
| 【Gene ID】： 1635 |
| 【Species Reactivity】： Human Mouse Rat (Gorilla) |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase.The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer.This protein uses zinc as a cofactor for its activity.Two transcript variants encoding different isoforms have been found for this gene.
Verified picture
