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Recombinant human GRP protein

Cat:P03575

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-148aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: GRP
【Full Name】: gastrin-releasing peptide
【Uniprot】: P07492
【Gene ID】: 2922
【Species Reactivity】: Human Mouse Rat (Pig Bovine A.thaliana)
【Mol Mass】: 16kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides.The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C.These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

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