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Recombinant human SLMO2 protein

Cat:P03578

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-194aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SLMO2
【Full Name】: slowmo homolog 2 (Drosophila)
【Uniprot】: Q9Y3B1
【Gene ID】: 51012
【Species Reactivity】: Human Mouse Rat (Bovine Pig Monkey)
【Mol Mass】: 21kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The cytoplasmic domains of integrins are essential for cell adhesion.The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain.The interaction between this protein and beta1 integrin is highly specific.Two isoforms of this protein are derived from alternatively spliced transcripts.The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain.The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

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