Summary:
Recombinant human ICA1L protein
Cat：P03585
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-180aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： ICA1L |
| 【Full Name】： islet cell autoantigen 1，69kDa-like |
| 【Uniprot】： Q8NDH6 |
| 【Gene ID】： 130026 |
| 【Species Reactivity】： Human Mouse Rat |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases.The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state.Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors.Mutations in this gene have been found in individuals with nephrotic syndrome, type 8.Alternate splicing results in multiple transcript variants.
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