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Recombinant human MAFG protein

Cat:P03589

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-162aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: MAFG
【Full Name】: v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
【Uniprot】: O15525
【Gene ID】: 4097
【Species Reactivity】: Human Mouse Rat (Bovine Chicken)
【Mol Mass】: 18kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]).NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490).Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins

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