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Recombinant human KCNE1 protein

Cat:P03604

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-129aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: KCNE1
【Full Name】: potassium voltage-gated channel,Isk-related family,member 1
【Uniprot】: P15382
【Gene ID】: 3753
【Species Reactivity】: Human Mouse (Pig Rat Gorilla)
【Mol Mass】: 15kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The product of this gene belongs to the potassium channel KCNE family.Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties.This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel.Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome.Alternatively spliced transcript variants encoding the same protein have been identified.

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