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Recombinant human VPS24 protein

Cat:P03605

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-222aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: VPS24
【Full Name】: vacuolar protein sorting 24 homolog (S. cerevisiae)
【Uniprot】: Q9Y3E7
【Gene ID】: 51652
【Species Reactivity】: Human Mouse Rat (Bovine Gorilla Zebrafish Monkey)
【Mol Mass】: 25kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway.This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB.This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.Alternative splicing results in multiple transcript variants.Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene

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