Summary:
Recombinant human CBX5 protein
Cat：P03606
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-191aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CBX5 |
| 【Full Name】： chromobox homolog 5 (HP1 alpha homolog，Drosophila) |
| 【Uniprot】： P45973 |
| 【Gene ID】： 23468 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 22kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family.The protein is enriched in the heterochromatin and associated with centromeres.The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins.The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins.The gene has a pseudogene located on chromosome 3.Multiple alternatively spliced variants, encoding the same protein, have been identified.
Verified picture
