Summary:
Recombinant human BID protein
Cat：P03626
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-195aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： BID |
| 【Full Name】： BH3 interacting domain death agonist |
| 【Uniprot】： P55957 |
| 【Gene ID】： 637 |
| 【Species Reactivity】： Human Mouse Rat (Pig Chicken) |
| 【Mol Mass】： 22kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2.The encoded protein is a member of the BCL-2 family of cell death regulators.It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Verified picture
