Summary:
Recombinant human UBE2C protein
Cat：P03639
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-179aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： UBE2C |
| 【Full Name】： ubiquitin-conjugating enzyme E2C |
| 【Uniprot】： O00762 |
| 【Gene ID】： 11065 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish) |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases.This gene encodes a member of the E2 ubiquitin-conjugating enzyme family.The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression.Multiple transcript variants encoding different isoforms have been found for this gene.Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
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