Summary:
Recombinant human RPS3 protein
Cat：P03649
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-243aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： RPS3 |
| 【Full Name】： ribosomal protein S3 |
| 【Uniprot】： P23396 |
| 【Gene ID】： 6188 |
| 【Species Reactivity】： Human Mouse Rat (A.thaliana) |
| 【Mol Mass】： 27kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated.The protein belongs to the S3P family of ribosomal proteins.Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage.The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus.Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed.This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively.As is typical for genes encoding ribosomal protei
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