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Recombinant human PMP2 protein

Cat:P03653

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-132aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PMP2
【Full Name】: peripheral myelin protein 2
【Uniprot】: P02689
【Gene ID】: 5375
【Species Reactivity】: Human Mouse Rat (Bovine)
【Mol Mass】: 15kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system.The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath.A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy.

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