Summary:
Recombinant human PAX6 protein
Cat：P03656
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-422aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PAX6 |
| 【Full Name】： paired box 6 |
| 【Uniprot】： P26367 |
| 【Gene ID】： 5080 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Zebrafish Fruit fly Chicken) |
| 【Mol Mass】： 47kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription.Activity of this protein is key in the development of neural tissues, particularly the eye.This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus.Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly.Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
Verified picture
