Summary:
Recombinant human NUDT4 protein
Cat：P03665
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-180aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： NUDT4 |
| 【Full Name】： nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| 【Uniprot】： Q9NZJ9 |
| 【Gene ID】： 11163 |
| 【Species Reactivity】： Human Mouse Rat (Gorilla A.thaliana) |
| 【Mol Mass】： 20kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates.The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences.Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking.Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined.Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing.
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