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Recombinant human RAB38 protein

Cat:P03729

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-211aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: RAB38
【Full Name】: RAB38,member RAS oncogene family
【Uniprot】: P57729
【Gene ID】: 23682
【Species Reactivity】: Human Mouse
【Mol Mass】: 24kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

May be involved in melanosomal transport and docking.Involved in the proper sorting of TYRP1.Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7.Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.Plays an important role in the control of melanin production and melanosome biogenesis.In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.

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