Summary:
Calcineurin B homologous protein 3
Cat：P03740
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-214aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： TESC |
| 【Full Name】： Calcineurin B homologous protein 3 |
| 【Uniprot】： Q96BS2 |
| 【Gene ID】： 54997 |
| 【Species Reactivity】： Human Mouse (Chicken) |
| 【Mol Mass】： 25kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity.Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane.Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage.Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.Also involved in granulocytic differentiation in a ERK-dependent manner.Inhibits the phosphatase activity of calcineurin.
Verified picture
