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Recombinant human ICT1 protein

Cat:P03764

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-206aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: ICT1
【Full Name】: immature colon carcinoma transcript 1
【Uniprot】: Q14197
【Gene ID】: 3396
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 24kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit.Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation.May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

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