Summary:
Recombinant human MLF1 protein
Cat：P03795
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-268aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： MLF1 |
| 【Full Name】： myeloid leukemia factor 1 |
| 【Uniprot】： P58340 |
| 【Gene ID】： 4291 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Chicken Gorilla) |
| 【Mol Mass】： 31kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation.Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels.Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Verified picture
