Summary:
Recombinant human CASP2 protein
Cat：P03812
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 153-431aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CASP2 |
| 【Full Name】： caspase 2，apoptosis-related cysteine peptidase |
| 【Uniprot】： P42575 |
| 【Gene ID】： 835 |
| 【Species Reactivity】： Human Mouse Rat (Chicken A.thaliana) |
| 【Mol Mass】： 31kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution.Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
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