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Recombinant human TCAP protein

Cat:P03853

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-167aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: TCAP
【Full Name】: Telethonin
【Uniprot】: O15273
【Gene ID】: 8557
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 20kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Sarcomere assembly is regulated by the muscle protein titin.Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere.It serves as a scaffold to which myofibrils and other muscle related proteins are attached.This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly.Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

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