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Recombinant human RHOA protein

Cat:P03866

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-193aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: RHOA
【Full Name】: ras homolog gene family,member A
【Uniprot】: P61586
【Gene ID】: 387
【Species Reactivity】: Human Mouse Rat (Bovine)
【Mol Mass】: 22kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.Overexpression of this gene is associated with tumor cell proliferation and metastasis.Multiple alternatively spliced variants have been identified.

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