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Recombinant human EHMT2 protein

Cat:P03883

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-350aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: EHMT2
【Full Name】: Histone-lysine N-methyltransferase EHMT2
【Uniprot】: Q96KQ7
【Gene ID】: 10919
【Species Reactivity】: Human Mouse
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a methyltransferase that methylates lysine residues of histone H3.Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription.This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus.Alternative splicing results in multiple transcript variants.

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