Summary:
Recombinant human PAIP2 protein
Cat：P03901
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-127aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： PAIP2 |
| 【Full Name】： Polyadenylate-binding protein-interacting protein 2 |
| 【Uniprot】： Q9BPZ3 |
| 【Gene ID】： 51247 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Chicken Gorilla) |
| 【Mol Mass】： 15kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs.Its inhibitory activity on translation is mediated via its action on PABPC1.Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1.Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Verified picture
