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Recombinant human HCN3 protein

Cat:P03916

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 162-446aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HCN3
【Full Name】: hyperpolarization activated cyclic nucleotide-gated potassium channel 3
【Uniprot】: Q9P1Z3
【Gene ID】: 57657
【Species Reactivity】: Human Mouse Rat
【Mol Mass】: 31kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels.HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity.HCN3 has been detected in the brain, but with less expression than other HCN channels.

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