Summary:
Recombinant human HSD17B8 protein
Cat：P03917
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-261aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： HSD17B8 |
| 【Full Name】： Estradiol 17-beta-dehydrogenase 8 |
| 【Uniprot】： Q92506 |
| 【Gene ID】： 7923 |
| 【Species Reactivity】： Human Mouse Rat (Pig) |
| 【Mol Mass】： 27kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens.It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone.However, the enzyme has some reductive activity and can synthesize estradiol from estrone.The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily.An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
Verified picture
