Summary:
Recombinant human KCNIP3 protein
Cat：P03934
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-256aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： KCNIP3 |
| 【Full Name】： Kv channel interacting protein 3，calsenilin |
| 【Uniprot】： Q9Y2W7 |
| 【Gene ID】： 30818 |
| 【Species Reactivity】： Human Mouse Rat (Bovine) |
| 【Mol Mass】： 29kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily.Members of this family are small calcium binding proteins containing EF-hand-like domains.They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium.The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins.Alternatively spliced transcript variants encoding different isoforms have been described.
Verified picture
