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Recombinant human NEIL1 protein

Cat:P03965

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-390aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NEIL1
【Full Name】: nei endonuclease VIII-like 1 (E. coli)
【Uniprot】: Q96FI4
【Gene ID】: 79661
【Species Reactivity】: Human Mouse
【Mol Mass】: 43kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases.The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines.Multiple transcript variants encoding different isoforms have been found for this gene.

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