Summary:
Recombinant human CD177 protein
Cat：P03978
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 88-437aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： CD177 |
| 【Full Name】： CD177 molecule |
| 【Uniprot】： Q8N6Q3 |
| 【Gene ID】： 57126 |
| 【Species Reactivity】： Human Mouse |
| 【Mol Mass】： 39kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation.The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration.Mutations in this gene are associated with myeloproliferative diseases.Over-expression of this gene has been found in patients with polycythemia rubra vera.Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis.A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
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