Summary:
Recombinant human SPA17 protein
Cat：P03983
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-152aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： SPA17 |
| 【Full Name】： sperm autoantigenic protein 17 |
| 【Uniprot】： Q15506 |
| 【Gene ID】： 53340 |
| 【Species Reactivity】： Human Mouse (Rabbit) |
| 【Mol Mass】： 17kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： No activity experimental data, to be verified. |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 2-7 days， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a protein present at the cell surface.The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif.The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion.The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte.Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis.A retrotransposed pseudogene is present on chromosome 10q22.
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