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Recombinant human NUDT11 protein

Cat:P03997

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-165aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NUDT11
【Full Name】: nudix (nucleoside diphosphate linked moiety X)-type motif 11
【Uniprot】: Q96G61
【Gene ID】: 55190
【Species Reactivity】: Human Mouse (Bovine A.thaliana)
【Mol Mass】: 18kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction.Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A.Also able to hydrolyze 5-phosphoribose 1-diphosphate.

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