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Recombinant human NVL protein

Cat:P04008

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 310-659aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NVL
【Full Name】: nuclear VCP-like
【Uniprot】: O15381
【Gene ID】: 4931
【Species Reactivity】: Human Mouse (A.thaliana)
【Mol Mass】: 38kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily.Multiple transcript variants encoding different isoforms have been found for this gene.Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus.The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

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