Summary:
Recombinant human SFXN1 protein
Cat：P04017
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-237aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： SFXN1 |
| 【Full Name】： sideroflexin 1 |
| 【Uniprot】： Q9H9B4 |
| 【Gene ID】： 94081 |
| 【Species Reactivity】： Human Mouse Rat (Bovine Pig Sheep) |
| 【Mol Mass】： 36kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778).Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).Transports both D-serine and L-serine (PubMed:30442778).Also able to transport other amino-acids, such as alanine (PubMed:30442778).May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity).
Verified picture
