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Recombinant human PDE4D protein

Cat:P04022

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-222aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PDE4D
【Full Name】: phosphodiesterase 4D,cAMP-specific (phosphodiesterase E3 dunce homolog,Drosophila)
【Uniprot】: Q08499
【Gene ID】: 5144
【Species Reactivity】: Human Mouse Rat
【Mol Mass】: 24kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene.The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types.This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

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