Summary:
Recombinant human STUB1 protein
Cat：P04057
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-304aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： STUB1 |
| 【Full Name】： STIP1 homology and U-box containing protein 1 |
| 【Uniprot】： Q9UNE7 |
| 【Gene ID】： 10273 |
| 【Species Reactivity】： Human Mouse (Chicken) |
| 【Mol Mass】： 33kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone.The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets.Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16.Alternative splicing results in multiple transcript variants.There is a pseudogene for this gene on chromosome 2.
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