Summary:
Recombinant human COPS8 protein
Cat：P04063
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-209aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： COPS8 |
| 【Full Name】： COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) |
| 【Uniprot】： Q99627 |
| 【Gene ID】： 10920 |
| 【Species Reactivity】： Human Mouse Rat (Gorilla) |
| 【Mol Mass】： 23kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways.The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome.COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Verified picture
