Summary:
Recombinant human EEF1D protein
Cat：P04066
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 298-647aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： EEF1D |
| 【Full Name】： eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| 【Uniprot】： P29692 |
| 【Gene ID】： 1936 |
| 【Species Reactivity】： Human Mouse Rat (Rabbit Bovine Sheep) |
| 【Mol Mass】： 38kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome.This subunit, delta, functions as guanine nucleotide exchange factor.It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat.This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins.Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
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