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Recombinant human SUNC1 protein

Cat:P04147

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-306aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: SUNC1
【Full Name】: Sad1 and UNC84 domain containing 1
【Uniprot】: Q8TAQ9
【Gene ID】: 256979
【Species Reactivity】: Human Mouse (Bovine)
【Mol Mass】: 34kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton.The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning.May be involved in nuclear remodeling during sperm head formation in spermatogenenis.A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.

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