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Recombinant human NASP protein

Cat:P04189

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 101-450aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NASP
【Full Name】: nuclear autoantigenic sperm protein (histone-binding)
【Uniprot】: P49321
【Gene ID】: 4678
【Species Reactivity】: Human Mouse Rat (Bovine Rabbit)
【Mol Mass】: 39kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Required for DNA replication, normal cell cycle progression and cell proliferation.Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity.NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.

Verified picture