Summary:
Recombinant human DOK4 protein
Cat：P04190
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-327aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： DOK4 |
| 【Full Name】： docking protein 4 |
| 【Uniprot】： Q8TEW6 |
| 【Gene ID】： 55715 |
| 【Species Reactivity】： Human Mouse (Gorilla) |
| 【Mol Mass】： 36kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins.They provide a docking platform for the assembly of multimolecular signaling complexes.DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity).Putative link with downstream effectors of RET in neuronal differentiation.May be involved in the regulation of the immune response induced by T-cells.
Verified picture
