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Recombinant human CBLC protein

Cat:P04199

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 126-475aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CBLC
【Full Name】: Cas-Br-M (murine) ecotropic retroviral transforming sequence c
【Uniprot】: Q9ULV8
【Gene ID】: 23624
【Species Reactivity】: Human Mouse Rat
【Mol Mass】: 39kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the Cbl family of E3 ubiquitin ligases.Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases.Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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