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Recombinant human CENPO protein

Cat:P04205

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-301aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: CENPO
【Full Name】: centromere protein O
【Uniprot】: Q9BU64
【Gene ID】: 79172
【Species Reactivity】: Human Mouse (Chicken Bovine)
【Mol Mass】: 33kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.Modulates the kinetochore-bound levels of NDC80 complex.

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