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Recombinant human MTCH2 protein

Cat:P04232

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-304aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: MTCH2
【Full Name】: mitochondrial carrier homolog 2 (C. elegans)
【Uniprot】: Q9Y6C9
【Gene ID】: 23788
【Species Reactivity】: Human Mouse (Gorilla Bovine)
【Mol Mass】: 33kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane.Members of this superfamily are involved in many metabolic pathways and cell functions.Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity.This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

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