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Recombinant human HCK protein

Cat:P04277

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-350aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HCK
【Full Name】: hemopoietic cell kinase
【Uniprot】: P08631
【Gene ID】: 3055
【Species Reactivity】: Human Mouse Rat
【Mol Mass】: 39kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

The protein encoded by this gene is a member of the Src family of tyrosine kinases.This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages.It may help couple the Fc receptor to the activation of the respiratory burst.In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

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