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Recombinant human PSMC5 protein

Cat:P04290

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-360aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: PSMC5
【Full Name】: proteasome (prosome,macropain) 26S subunit ATPase 5
【Uniprot】: P62195
【Gene ID】: 5705
【Species Reactivity】: Human Mouse Rat (Pig Bovine)
【Mol Mass】: 40kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Component of tHumane 26S proteasome, a multiprotein complex involved in tHumane ATP-dependent degradation of ubiquitinated proteins.THumanis complex plays a key role in tHumane maintenance of protein Humanomeostasis by removing misfolded or damaged proteins, wHumanicHuman could impair cellular functions, and by removing proteins wHumanose functions are no longer required.THumanerefore, tHumane proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.PSMC5 belongs to tHumane HumaneteroHumanexameric ring of AAA (ATPases associated witHuman diverse cellular activities) proteins tHumanat unfolds ubiquitinated target proteins tHumanat are concurrently translocated into a proteolytic cHumanamber and degraded into peptides.

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