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Recombinant human NSFL1C protein

Cat:P04318

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 1-371aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: NSFL1C
【Full Name】: NSFL1 (p97) cofactor (p47)
【Uniprot】: Q9UNZ2
【Gene ID】: 55968
【Species Reactivity】: Human Mouse Rat (Bovine Gorilla Chicken)
【Mol Mass】: 41kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: No activity experimental data, to be verified.
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Reduces tHumane ATPase activity of VCP (By similarity).Necessary for tHumane fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity).May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity).InHumanibits tHumane activity of CTSL (in vitro).TogetHumaner witHuman UBXN2B/p37, regulates tHumane centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in propHumanase.Also, regulates spindle orientation during mitosis.

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